Everything You Need to Know About Altitude Sickness Pills in Peru

If you’re planning a Peru trip, the stunning views of Machu Picchu are likely at the top of your bucket list. But before you embark on your adventure, it’s essential to prepare for the challenges of high altitude. If you’re wondering how to avoid altitude sickness in Peru, preparation is essential and using altitude sickness pills, such as acetazolamide, will help to prevent or minimize symptoms. Here’s everything you need to know about them!

What Is Altitude Sickness?

Altitude sickness, also locally known as “Soroche,” occurs when your body struggles to adjust to lower oxygen levels at high altitudes. Common symptoms include headaches, dizziness, nausea, shortness of breath, and fatigue. It’s not fun, especially when you’re trying to enjoy the breathtaking Andes!

Cusco vs. Aguas Calientes vs. Machu Picchu: Altitude Matters!
  • Cusco altitude sits at a whopping 3,399 meters (11,152 feet) above sea level. This is where most travelers start feeling the effects of high altitude, and all travelers will arrive in Cusco first.
  • Aguas Calientes, the gateway town to Machu Picchu, is significantly lower at 2,040 meters (6,692 feet).
  • The Machu Picchu archaeological site itself is at 2,430 meters (7,972 feet), making the Machu Picchu elevation much more manageable compared to Cusco.

The sharp altitude difference between Cusco and Aguas Calientes often makes Cusco the trickiest part of the journey for your body to adjust to. Planning a few days to acclimatize in Cusco before heading to Machu Picchu can make a world of difference.

What Are Altitude Sickness Pills, and How Do They Work?

Altitude sickness pills like acetazolamide (brand name: Diamox) help your body adapt to high altitudes faster. They work by:

  • Increasing your breathing rate, which helps get more oxygen into your system.
  • Reducing fluid buildup in your brain and lungs, which can contribute to severe altitude sickness symptoms.

For best results, you need to start taking acetazolamide a day or two before ascending to high altitudes and continue while you remain at altitude.

Are Altitude Sickness Pills Safe?

For most people, acetazolamide is safe when used as directed. However, it’s important to:

  • Consult your doctor before your trip, especially if you have allergies to sulfa drugs or other medical conditions.
  • Be aware of mild side effects like tingling sensations in your fingers or toes, changes in taste, or frequent urination.

In North America, altitude sickness pills must be prescribed by your family doctor. If you’re already in Peru, you can often find them at pharmacies without a prescription. However, it’s still safer to seek guidance from a healthcare professional before taking them.

Rest and Acclimatization: Your Best Defense

While pills can help, the best way to prevent altitude sickness in Peru is by allowing your body time to adjust. Spend a couple of days resting and exploring Cusco at a leisurely pace before diving into more physically demanding activities like trekking or visiting Machu Picchu. This gives your body a chance to adapt naturally.

Pro Tip: Try Coca Candy

Locals swear by coca leaves, which can be chewed or consumed as tea to help with altitude sickness. But a more traveler-friendly option, you can also find coca candy. Check out this post about Coca Candy for more details!

Altitude sickness doesn’t have to ruin your adventure. By planning ahead, allowing time to acclimate, and consulting your doctor about these pills, you can focus on the incredible experience of exploring regions like Machu Picchu and their surroundings!

PERSONALIZED TRIP PLANNING

From seamless private transfers and scenic train bookings to expert local planning and tailored pacing across Peru, we design 100% private, handcrafted journeys built around your travel style.

Custom Pacing & Beating the Crowds: Private schedules that let you adjust comfortably to high altitudes and experience iconic sights outside the busiest peak hours.

Dedicated English-Speaking Point of Contact: Direct, speedy communication before and throughout your entire trip with a Canadian expat and dual citizen living in Peru.

Local Peruvian & Expat Leadership: A balanced approach combining deep local heritage and insider connections with North American travel standards.

Travel That Gives Back: All profits stay in Peru, with a portion directly supporting local community youth through Jóvenes con Propósito.

Request a Custom Peru Itinerary

WHAT PEOPLE ARE SAYING ABOUT OUR PERU TREKS & TOURS

View More Testimonials